Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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2,221 – 2,235 of 6,680 results

2,221

Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 25 MG

Imeglimin hydrochloride (EMD 387008) is an oral glucose-lowering agent that reduces reactive oxygen species (ROS) production, increases mitochondrial DNA, and improves mitochondrial function. This compound appears as a white to off-white solid.

Oral glucose-lowering agent
Reduces reactive oxygen species (ROS) production
Increases mitochondrial DNA
Improves mitochondrial function
Soluble in H2O (≥ 50 mg/mL)
Soluble in DMSO (25 mg/mL)

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2,222

Medchemexpress LLC SB-269970 hydrochloride | 261901-57-9 | C18H29ClN2O3S | 5 MG

SB-269970 hydrochloride is a potent, selective, and brain-penetrant 5-HT7 receptor antagonist with a pKi of 8.3. It exhibits >50-fold selectivity against other 5-HT receptors.

Potent and selective 5-HT7 receptor antagonist
Brain-penetrant
Demonstrates greater than 50-fold selectivity against other 5-HT receptors
Significantly blocks amphetamine and ketamine-induced hyperactivity in animal models

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2,223

Medchemexpress LLC LY3020371 hydrochloride | 1377615-44-5 | 99.2% | 395.81 | 5 MG

LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, potently blocks cAMP formation with IC50 of 16.2 nM. It exerts an antidepressant-like signature in vivo.

Potent, selective mGlu2/3 receptor antagonist.
Ki values of 5.3 nM for mGluR2 and 2.5 nM for mGluR3.
Blocks cAMP formation with an IC50 of 16.2 nM.
Exerts an antidepressant-like signature in vivo.
Blocks agonist-suppressed Ca2+ oscillations (IC50=34 nM) and in hippocampal slices (IC50=46 nM).
Intravenous injection leads to effective mGlu2/3 receptor blockade in rat cerebrospinal fluid.
Promotes wakefulness, reducing NREM sleep in Wistar rats.
Available in various sizes and forms.
High purity (99.18%).
Detailed documentation provided.
Solubility and dissolution protocols available.

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2,224

Medchemexpress LLC Ots186935 (hydrochloride) | 99.6% | 522.31 | 100 MG

OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. It significantly inhibits tumor growth in mouse xenograft models without detectable toxicity and regulates the production of γ-H2AX in cancer cells. This compound has shown growth suppressive effects in human cancer cell line derived xenograft models.

Potent SUV39H2 inhibitor
Inhibits tumor growth in mouse xenograft models
Regulates production of γ-H2AX in cancer cells
Shows significant inhibition of tumor growth without detectable toxicity
Inhibits A549 cell growth with an IC50 of 0.67 μM
Exhibits growth suppressive effects in human cancer cell line derived xenograft models

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2,225

Medchemexpress LLC 7H-pyrrolo[2,3-d]pyrimidin-4-amine, N-butyl-N-ethyl-2,5,6-trimethyl-7-(trimethylphenyl) hydrochloride | 220953-69-5 | MFCD05664721 | 99.9% | 415.01 g/mol | C24H35ClN4 | 50 MG

Antalarmin hydrochloride is a research-grade, non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist supplied as a white to light yellow solid for preclinical research. It is used to study stress-response pathways, CRH/CRF signaling, anxiety-like behavior, and inflammation models. The compound is provided at high purity and supplied in small mg-scale pack sizes suitable for laboratory use.

Non-peptide CRHR1 antagonist used in stress and neuroendocrine research.
High purity for reliable experimental results.
Solid form, easy to weigh and formulate.
Available in mg-scale pack sizes for preclinical studies.
Includes datasheet, certificate of analysis, and safety data sheet documentation.

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2,226

Medchemexpress LLC Ninhydrin | 485-47-2 | 99.99% | 1 ML

Ninhydrin is a chromogenic analytical probe utilized for the quantification of amino acids and proteins. It is widely employed in amino acid analysis of proteins, where most amino acids, excluding proline, undergo hydrolysis and react with ninhydrin, allowing for their colorimetric quantification following chromatographic separation. Ninhydrin interacts with primary and secondary amines to yield a distinctive blue or purple reaction product, diketohydrindylidene-diketohydrindamine.

Functions as a chromogenic analytical probe.
Enables quantification of amino acids.
Facilitates quantification of proteins.
Reacts with most amino acids (excluding proline).
Permits colorimetric quantification post-chromatographic separation.
Interacts with primary and secondary amines.
Generates a blue or purple reaction product.

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2,227

Medchemexpress LLC SCH-23390 (hydrochloride) | 125941-87-9 | 99.8% | 324.24 | 100 MG

SCH-23390 (hydrochloride) | 125941-87-9 | 99.8% | 324.24 | 100 MG

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2,228

Medchemexpress LLC SKF-34288 hydrochloride (3-Mercaptopicolinic acid hydrochloride) | 320386-54-7 | 98.6% | 100 MG

SKF-34288 hydrochloride (3-Mercaptopicolinic acid) is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor with a Ki of 2-9 μM. It acts as a potent hypoglycemic agent by inhibiting glucose synthesis and also inhibits Asn metabolism, leading to an increase in amino acids and amides.

Orally active PEPCK inhibitor (Ki: 2-9 μM)
Potent hypoglycemic agent that inhibits glucose synthesis
Inhibits Asn metabolism
Increases amino acids and amides
Reduces blood glucose in starved rats
Neutralizes Salbutamol-mediated hyperglycaemia in rabbits
Reduces pyruvate-induced blood glucose level in rats
Inhibits C2C12 cell proliferation
Induces myogenic differentiation of C2C12 cells

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2,229

Medchemexpress LLC PhiKan 083 hydrochlo | 1050480-30-2 | 99.3% | 274.79 | 10 MG

PhiKan 083 hydrochloride is a carbazole derivative that functions as a p53 Y220C stabilizer. It binds to the surface cavity of the Y220C (a p53 mutant) with a Kd of 167 μM and demonstrates a relative binding affinity (Kd) of 150 μM in Ln229 cells. This compound has been shown to slow down the thermal denaturation rate of p53 Y220C.

Binds to the surface cavity of p53 Y220C mutant.
Stabilizes p53 Y220C.
Exhibits a Kd of 167 μM for p53 Y220C.
Shows a relative binding affinity of 150 μM in Ln229 cells.
Slows the thermal denaturation rate.
Reduces cell viability of engineered Ln229 cell variants.
Enhances pro-apoptotic activity in Ln229 cells when combined with NSC 123127.

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2,230

Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.1% | 321.93 | 25 MG

Leelamine hydrochloride is a tricyclic diterpene molecule extracted from the bark of pine trees. It acts as a cannabinoid receptor type 1 (CB1) agonist and an inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells. Its activity is not affected by androgen receptor status, and it suppresses the transcriptional activity of the androgen receptor.

Tricyclic diterpene molecule
Extracted from the bark of pine trees
Cannabinoid receptor type 1 (CB1) agonist
Inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells
Suppresses transcriptional activity of androgen receptor
Appearance: solid
Color: white to off-white
For research use only

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2,231

Medchemexpress LLC NNMT-IN-6 hydrochloride | 3031756-18-7 | 98.2% | C25H30ClN7O5 | 10MG

NNMT-IN-6 hydrochloride is the hydrochloride salt of a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) intended for research use. It exhibits in vitro inhibitory activity (IC50 = 1.41 μM; Kd = 5.6 μM) and is supplied as a high-purity solid with documented solubility and storage recommendations for biochemical and cellular assays.

High purity (98.2%).
Confirmed NNMT inhibitory activity (IC50 = 1.41 μM; Kd = 5.6 μM).
Hydrochloride salt form for improved solubility.
Validated solubility in DMSO and water (250 mg/mL with sonication).
Suitable for biochemical and cellular assays targeting NNMT.
Recommended sealed storage away from moisture, with solvent stability guidelines.

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2,232

Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 5 G

Trazodone hydrochloride is a triazolopyridine derivative that acts as a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates anti-depressant and anti-insomnious activity by antagonizing α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects. It is suitable for various laboratory applications and research.

Exhibits anti-depressant and anti-insomnious activity
Acts as an antagonist against α1- and α2-adrenergic receptors
Antagonizes histamine H1 receptors
Demonstrates minimal anticholinergic effects
Binds to 5-HT1A receptor
Reduces expression of neuroinflammatory markers
Increases mRNA expression of BDNF and CREB

Pricing & Availability

2,233

Medchemexpress LLC Viloxazine hydrochloride | 35604-67-2 | MFCD00661100 | 98.9% | 273.75 g/mol | C13H20ClNO3 | 50MG

Viloxazine hydrochloride is a research-grade small molecule used as a selective norepinephrine transporter (NET) inhibitor and a modulator of serotonin (5-HT) receptors. Presented as the hydrochloride salt (CAS 35604-67-2) and supplied for preclinical laboratory use, it is commonly employed as a tool compound in studies of norepinephrine and serotonin signaling and in ADHD-related research.

Research-grade hydrochloride salt with defined purity for laboratory use.
Selective norepinephrine transporter inhibitor activity (IC50 = 0.26 μM).
Modulates 5-HT receptors, including 5-HT2B antagonist and 5-HT2C agonist actions.
Available in small pack sizes suitable for assays, including a 50 mg pack.
Provided with molecular and analytical data to support traceability and reproducibility.

Pricing & Availability

2,234

Medchemexpress LLC Abeprazan hydrochloride | 1902954-87-3 | 99.9% | 446.87 | 50 MG

Abeprazan hydrochloride (DWP14012 hydrochloride) is a potassium-competitive acid blocker that inhibits H+, K+- ATPase through reversible potassium-competitive ionic binding without requiring acid activation. It is being developed as a potential alternative to proton pump inhibitors for treating acid-related diseases.

Potassium-competitive acid blocker.
Inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding.
Does not require acid activation for its inhibitory mechanism.
Developed as a potential alternative for proton pump inhibitors.
Inhibits acid secretion in a dose-dependent manner in in vivo studies.
Efficacy is equal to or greater than that of vonoprazan in various in vivo studies.

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2,235

Medchemexpress LLC Sultopride hydrochloride | 23694-17-9 | MFCD01319147 | 99.9% | 390.93 | C17H27ClN2O4S | 10 MG

Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective dopamine D2 receptor antagonist supplied as a white to off-white solid for laboratory research applications. It is provided at high reported purity and in small pack sizes for bench-top experiments.

Selective dopamine D2 receptor antagonist.
High purity (≈99.9%).
White to off-white solid physical form.
CAS number 23694-17-9.
Molecular weight 390.93 g/mol.
Available in small pack sizes, including 10 MG.
Intended for research use only; not for human or clinical use.
Storage: 4°C, sealed and away from moisture; in solvent: -80°C for 6 months, -20°C for 1 month.

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Alcohols and polyols

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Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SB-269970 hydrochloride | 261901-57-9 | C18H29ClN2O3S | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC LY3020371 hydrochloride | 1377615-44-5 | 99.2% | 395.81 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ots186935 (hydrochloride) | 99.6% | 522.31 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ninhydrin | 485-47-2 | 99.99% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SCH-23390 (hydrochloride) | 125941-87-9 | 99.8% | 324.24 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SKF-34288 hydrochloride (3-Mercaptopicolinic acid hydrochloride) | 320386-54-7 | 98.6% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PhiKan 083 hydrochlo | 1050480-30-2 | 99.3% | 274.79 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.1% | 321.93 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NNMT-IN-6 hydrochloride | 3031756-18-7 | 98.2% | C25H30ClN7O5 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Viloxazine hydrochloride | 35604-67-2 | MFCD00661100 | 98.9% | 273.75 g/mol | C13H20ClNO3 | 50MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Abeprazan hydrochloride | 1902954-87-3 | 99.9% | 446.87 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sultopride hydrochloride | 23694-17-9 | MFCD01319147 | 99.9% | 390.93 | C17H27ClN2O4S | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More